Studies on D-Ribose Derivatives. II. Preparation of 2, 3Di-O-acetyl-5-deoxy-5-iodo-D-ribofuranosyl Chloride from 5-O-Trityl-D-ribose
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منابع مشابه
5-O-Acetyl-d-ribono-1,4-lactone
The title compound, C(7)H(10)O(6), was obtained from a regioselective enzyme-catalysed acyl-ation of d-ribono-1,4-lactone. The five-membered ring of the acyl-ated sugar shows an envelope conformation. In the crystal, the mol-ecules are linked by inter-molecular O-H⋯O hydrogen-bonds, forming a one-dimensional polymeric structure parallel to [010]. In addition, packing analysis shows stacking alo...
متن کامل1,2,3-Tri-O-acetyl-5-deoxy-d-ribofuranose
The title compound, C(11)H(16)O(7), was obtained from the breakage reaction of the glycosidic bond of 5'-de-oxy-2',3'-diacetyl-inosine. The ribofuran-ose ring has a C2-exo, C3-endo twist configuration. No alteration of the relative configuration compared with d-(-)-ribose is observed.
متن کاملPreparative scale enzymatic synthesis of D-sedoheptulose-7-phosphate from -hydroxypyruvate and D-ribose-5-phosphate
An enzymatic method for ready access to D-sedoheptulose-7-phosphate on a preparative scale was developed, based on the irreversible transketolase-catalyzed reaction: β-hydroxypyruvate + D-ribose-5phosphate → D-sedoheptulose-7-phosphate. D-Sedoheptulose-7-phosphate disodium salt was obtained in 81% overall yield determined using a standard curve obtained by LC/MS/MS.
متن کاملCharacterization of 5-chloro-5-deoxy-D-ribose 1-dehydrogenase in chloroethylmalonyl coenzyme A biosynthesis: substrate and reaction profiling.
SalM is a short-chain dehydrogenase/reductase enzyme from the marine actinomycete Salinispora tropica that is involved in the biosynthesis of chloroethylmalonyl-CoA, a novel halogenated polyketide synthase extender unit of the proteasome inhibitor salinosporamide A. SalM was heterologously overexpressed in Escherichia coli and characterized in vitro for its substrate specificity, kinetics, and ...
متن کاملATTEMPTED SYNTHESIS OF 5' - DEOXY - 5' - PHOSPHONO - ISOCYTIDINE SYNTHESIS OF PHOSPHONIC ACID DERIVATIVES OF ACYCLO - NUCLEOSIDES. PREPARATION OF 1- ?- D- ARABINOFURANOSYL PYRIMIDINES
The synthesis of 5' - deoxynucleoside 5' - phosphonates which contains a 5' - CP bond in place of the 5' -COP bond of the naturally occuring nucleotides is described. The preparation of phosphonate derivatives of acyclo - nucleosides and a simple method for the conversion of 1-? -D-ribofuranosyl pyrimidines to the corresponding 1-? -D-arabinofuranosyl pyrimidines are also explained
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ژورنال
عنوان ژورنال: Nippon kagaku zassi
سال: 1959
ISSN: 0369-5387,2185-0917
DOI: 10.1246/nikkashi1948.80.2_200